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              弲ŵ״BƼiptacopanҹѪ쵰(PNH)Ч

              2021-06-15 16:10:15Դ: վĶ:633994

              ŵNovartisչiptacopanLNP023ҹѪ쵰PNHһ2ٴоNCT03896152ݡʾǰûнܹC5ƼPNHУiptacopanҩ12ܣѪںѪѪʵ˿ٺͳ־õѪơоУiptacopanãûİȫԷ֡

              µоʾiptacopanΪҩƷPNHDZǰڡҶѪҺѧϵһűǩIIоNCT03439839Ľʾڽܱ׼ƷC5ƼSoliris[eculizumab]ƵлѪPNHУiptacopanΪƷѪҺѧӦͼ־һ洦ֹͣSolirisƵĻмά֡

              PNHһֺġΣѪҺDzѪѪ˨γɺ͹蹦𣬵ƶѪƣͺ˥֢״Щ֢״Ӱ컼ߵʹõǰĿC5׼ƷƣܴһPNHȻƶѪѪ

              iptacopanѧṹʽͼƬԴmedchemexpress.com)

              iptacopanһ״ģfirst-in-classڷǿЧѡԡСӡBƼBDzϵͳ;Ĺؼ˿ᵰøĿǰiptacopanƲϵͳۡδһЩ༲ҹѪ쵰PNHIgAIgANC3С򼲲C3GǵѪ֢ۺaHUSĤMN

              IIʾiptacopanIgAN˵ȶܡC3G˹ƵС˹ʣeGFR½ٶȲȶܡ

              iptacopanŵಡȽʲбDz;Dz༲CDRDĹؼءǰiptacopanѻFDAŷEMAPNHC3GŶҩʸODDEMAIgANODDFDAPNHͻҩʸBTDEMAC3GҩʸPRIME

              弤-PNHƵưе㣨ͼƬԴףPMC6060635

              NCT03896152һġűǩ2СΧ2о13ǰ3лѪδܲƵPNH˻пչiptacopanΪҩƷЧȫԡҩѧ/ҩЧѧ

              ʾ12ƵĻߣn=11ﵽҪյ㣺øLDHˮƽٽ60%LDHѪѪ־Ҫǣ1߽˵κϸRBCע⣬໼12ڼûѪߵѪ־ҲֳƣPNHRBCӣѪںѪѪõȫơ

              12ڼ䣬ûбصIJ¼Ѫ˨˨¼ûзİȫԽ212ǰֹͣiptacopanƣ1ڷͷʹ1ǰڵϸ֢񻯶ҽġIJӦΪͷʹ31%ʣ15%Ѫøߣ15%ԣ15%ʹ15%ȣߣ15%ϺȾ15%

              ŵȫҩ↑ܼϯҽƹJohn Tsaiʾ“PNHһֺΣѪҺҪµƷЩһǿiptacopanΪһǰ;ĿڷҩƷDZǺܸڽе3ом̽iptacopanΪPNH±׼DZ”

              Դ https://news.bioon.com/article/6787991.html







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